Emergency crews are at the scene of a serious incident on the Warrego Highway at Karalee, where a truck and pedestrian have collided.
A Queensland Police Service spokesperson says both westbound lanes heading to Toowoomba are closed, and motorists are being told to avoid the area.
The incident happened just before 12pm, near the Bremer River Bridge.
A Queensland Ambulance Service spokesperson couldn't comment on the condition of the driver or pedestrian, saying it is too early at this stage.
Investigations are continuing.
More to come.